Sunday, August 2, 2009

Sunday August 2, 2009
Why Arixtra doesn't cause HIT (Heparin induced thrombocytopenia)






ARIXTRA (Fondaparinux) is not a heparin. ARIXTRA is the first and only pentasaccharide antithrombotic agent inhibiting only factor Xa
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1 comment:

  1. Rich SavelAugust 2, 2009 at 12:45 PM

    hit is caused by an antibody against heparin and platelet factor 4. the fc receptor activates platelets, and consumes them. if it doens't have the right epitope, the antibody won't be able to bind to the heparin and platelet factor 4, and activate the platelets.

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